Synthesis and Pharmacological Properties of Glutamic Acid Amides: a Review
نویسندگان
چکیده
Amide is a derivative of carboxylic acids with a general formula of RCONH2, where R is hydrogen or an alkyl or an aryl radical. The amides are abundant in life, as proteins play a vital role in almost all biological processes. They present in many pharmaceutical substances. An in-depth analysis of the Comprehensive Medicinal Chemistry database reveals that the carboxamide group appears in more than 25% of all known drugs [1]. Abbreviations used in the text are listed in Table 1. Examples of coupling reagents discussed in this review are added in Table 2. SYNTHESIS AND PHARMACOLOGICAL PROPERTIES OF GLUTAMIC ACID AMIDES: A REVIEW
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